Philip Scheltens Selected Research

Threonine (L-Threonine)

1/2022	P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles.
1/2018	Disease-related determinants are associated with mortality in dementia due to Alzheimer's disease.
3/2015	Influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.
10/2012	Injury markers predict time to dementia in subjects with MCI and amyloid pathology.
7/2010	Dementia mimicking Alzheimer's disease Owing to a tau mutation: CSF and PET findings.
2/2010	Amyloid-beta(1-42), total tau, and phosphorylated tau as cerebrospinal fluid biomarkers for the diagnosis of Alzheimer disease.
1/2010	BACE1 activity in cerebrospinal fluid and its relation to markers of AD pathology.
1/2010	Diagnostic impact of CSF biomarkers in a local hospital memory clinic.
1/2010	Joint effect of hypertension and APOE genotype on CSF biomarkers for Alzheimer's disease.

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Philip Scheltens Research Topics

Disease

310	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 08/2002
174	Dementia (Dementias) 10/2022 - 09/2003
156	Cognitive Dysfunction 10/2022 - 03/2002
82	Atrophy 01/2022 - 03/2002
23	Disease Progression 01/2022 - 06/2012
18	Frontotemporal Dementia (Semantic Dementia) 01/2020 - 09/2003
11	Amyloid Plaque 01/2021 - 01/2011
9	Inflammation (Inflammations) 01/2022 - 08/2002
8	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2020 - 09/2003
8	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 01/2018 - 01/2003
5	Amyloidosis 06/2022 - 03/2013
5	Genetic Risk Score 01/2021 - 01/2016
5	Parkinson Disease (Parkinson's Disease) 01/2021 - 01/2015
5	Hypertension (High Blood Pressure) 01/2010 - 07/2004
4	Memory Disorders (Memory Loss) 01/2021 - 01/2006
4	Pathologic Processes 10/2020 - 12/2004
4	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2019 - 11/2009
4	Infarction (Infarctions) 01/2019 - 01/2007
3	Ovarian Neoplasms (Ovarian Cancer) 06/2021 - 01/2018
3	Breast Neoplasms (Breast Cancer) 06/2021 - 01/2018
3	Multiple Sclerosis 06/2021 - 01/2017
3	Tauopathies 01/2021 - 09/2003
3	Edema (Dropsy) 01/2018 - 07/2011
3	Neurobehavioral Manifestations 01/2018 - 12/2011
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/2017 - 01/2006
3	Cerebral Small Vessel Diseases 01/2015 - 10/2012
2	Infections 01/2022 - 04/2010
2	Myocardial Infarction 06/2021 - 01/2019
2	Sepsis (Septicemia) 06/2021 - 01/2019
2	Malnutrition (Nutritional Deficiencies) 01/2020 - 05/2019
2	Primary Progressive Aphasia 01/2020 - 11/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 11/2009
2	Vascular Diseases (Vascular Disease) 01/2020 - 01/2006
2	Neoplasms (Cancer) 01/2019 - 01/2018
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2019 - 12/2015
2	Cerebrovascular Trauma 01/2019 - 01/2019
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 12/2018 - 11/2013
2	Neuroinflammatory Diseases 05/2018 - 01/2016
2	Synucleinopathies 01/2018 - 01/2010
2	Lewy Body Disease (Lewy Body Dementia) 08/2017 - 07/2013
2	Corticobasal Degeneration 08/2017 - 01/2016

Drug/Important Bio-Agent (IBA)

196	Biomarkers (Surrogate Marker)IBA 10/2022 - 01/2003
157	Amyloid (Amyloid Fibrils)IBA 10/2022 - 01/2006
59	Apolipoproteins E (ApoE)IBA 01/2022 - 03/2002
36	Pemetrexed (MTA)FDA Link 01/2020 - 07/2004
28	Amyloid beta-PeptidesIBA 12/2021 - 07/2005
26	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2006
24	ApolipoproteinsIBA 01/2022 - 03/2002
16	Biological ProductsIBA 10/2022 - 01/2002
13	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2006
11	Pharmaceutical PreparationsIBA 11/2021 - 05/2011
11	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 01/2021 - 12/2017
9	Threonine (L-Threonine)FDA Link 01/2022 - 01/2010
9	Peptides (Polypeptides)IBA 06/2021 - 09/2013
8	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2019 - 08/2010
6	Cholinergic Agents (Cholinergics)IBA 01/2022 - 12/2004
6	Blood Proteins (Serum Proteins)IBA 01/2021 - 01/2018
6	EnzymesIBA 01/2020 - 11/2009
5	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2022 - 01/2006
5	NeurograninIBA 10/2021 - 10/2015
4	Galantamine (Galanthamine)FDA LinkGeneric 01/2022 - 01/2006
4	flutemetamolIBA 01/2022 - 01/2017
4	Memantine (Namenda)FDA Link 10/2021 - 01/2004
4	DNA (Deoxyribonucleic Acid)IBA 10/2021 - 01/2014
4	Phosphotransferases (Kinase)IBA 01/2021 - 07/2014
4	HomocysteineIBA 10/2020 - 06/2007
4	Retinaldehyde (Retinal)IBA 12/2019 - 01/2018
4	ImmunosorbentsIBA 01/2019 - 11/2009
4	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2012 - 01/2012
3	IceIBA 06/2021 - 01/2018
3	florbetapirIBA 01/2021 - 01/2019
3	HDL LipoproteinsIBA 01/2021 - 05/2008
3	Folic Acid (Vitamin M)FDA LinkGeneric 10/2020 - 01/2015
3	IronIBA 10/2020 - 12/2007
3	UridineIBA 01/2020 - 01/2015
3	Antihypertensive Agents (Antihypertensives)IBA 01/2015 - 01/2006
3	PK 11195 (PK11195)IBA 01/2013 - 09/2007
3	Verapamil (Calan)FDA LinkGeneric 10/2012 - 01/2012
3	2- (1- (6- ((2- fluoroethyl)(methyl)amino)- 2- naphthyl)ethylidene)malononitrileIBA 06/2012 - 02/2009
2	Glial Fibrillary Acidic ProteinIBA 01/2022 - 01/2020
2	Indicators and Reagents (Reagents)IBA 10/2021 - 07/2013
2	Chitinase-3-Like Protein 1IBA 10/2021 - 09/2015
2	VitaminsIBA 10/2020 - 01/2015
2	Triglycerides (Triacylglycerol)IBA 10/2020 - 05/2008
2	LipidsIBA 10/2020 - 01/2014
2	Complement System Proteins (Complement)IBA 01/2020 - 01/2019
2	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 10/2019 - 01/2018
2	PhosphopeptidesIBA 01/2019 - 01/2018
2	glutaminyl-peptide cyclotransferaseIBA 10/2018 - 06/2017
2	gantenerumabIBA 01/2018 - 12/2017
2	Monoclonal AntibodiesIBA 01/2018 - 01/2013
2	bapineuzumabIBA 01/2018 - 05/2016
2	pleiotrophin (HARP)IBA 10/2017 - 02/2015
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2017 - 01/2014

Therapy/Procedure

14	Activities of Daily Living (ADL) 01/2021 - 01/2010
12	Therapeutics 01/2021 - 07/2004
8	Institutionalization (Institutionalized Persons) 01/2022 - 01/2012
7	Secondary Prevention 10/2020 - 04/2006
3	Home Nursing (Nursing, Home) 05/2015 - 01/2005
2	Precision Medicine 11/2019 - 12/2018